Thursday, January 31, 2013

President Kibaki gives Coast region its first fully-fledged university


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2 NFL seasons since agreement, still no HGH tests

FILE - The House Oversight and Government Reform Committee, led by Chairman Darrell Issa, R-Calif., right, considers whether to hold Attorney General Eric Holder in contempt of Congress, on Capitol Hill in Washington, in this June 20, 2012 file photo. Ranking Democrat Elijah Cummings of Maryland is at left. House Oversight and Government Reform Committee chairman Darrell Issa, a California Republican, and ranking Democrat Elijah Cummings of Maryland wrote NFLPA head DeMaurice Smith Monday Jan.28, 2013 to chastise the union for standing in the way of HGH testing and to warn that they might ask players to testify on Capitol Hill. (AP Photo/J. Scott Applewhite, )ile

FILE - The House Oversight and Government Reform Committee, led by Chairman Darrell Issa, R-Calif., right, considers whether to hold Attorney General Eric Holder in contempt of Congress, on Capitol Hill in Washington, in this June 20, 2012 file photo. Ranking Democrat Elijah Cummings of Maryland is at left. House Oversight and Government Reform Committee chairman Darrell Issa, a California Republican, and ranking Democrat Elijah Cummings of Maryland wrote NFLPA head DeMaurice Smith Monday Jan.28, 2013 to chastise the union for standing in the way of HGH testing and to warn that they might ask players to testify on Capitol Hill. (AP Photo/J. Scott Applewhite, )ile

FILE - NFL players union chief DeMaurice Smith pauses as he speaks during a news conference outside their headquarters, in this May 24, 2012 file photo taken in Washington. House Oversight and Government Reform Committee chairman Darrell Issa, a California Republican, and ranking Democrat Elijah Cummings of Maryland wrote NFLPA head DeMaurice Smith Monday Jan.28, 2013 to chastise the union for standing in the way of HGH testing and to warn that they might ask players to testify on Capitol Hill. (AP Photo/Carolyn Kaster, File)

(AP) ? Baltimore Ravens defensive end Arthur Jones is among those NFL players who want the league and the union to finally agree on a way to do blood testing for human growth hormone.

"I hope guys wouldn't be cheating. That's why you do all this extra work and extra training. Unfortunately, there are probably a few guys, a handful maybe, that are on it. It's unfortunate. It takes away from the sport," Jones said.

"It would be fair to do blood testing," Jones added. "Hopefully they figure it out."

When Jones and the Ravens face the San Francisco 49ers in the Super Bowl on Sunday, two complete seasons will have come and gone without a single HGH test being administered, even though the league and the NFL Players Association paved the way for it in the 10-year collective bargaining agreement they signed in August 2011.

Since then, the sides have haggled over various elements, primarily the union's insistence that it needs more information about the validity of a test that is used by Olympic sports and Major League Baseball. HGH is a banned performance-enhancing drug that is hard to detect and has been linked to health problems such as diabetes, cardiac dysfunction and arthritis.

"If there are guys using (HGH), there definitely needs to be action taken against it, and it needs to be out of (the sport)," Ravens backup quarterback Tyrod Taylor said. "I'm pretty sure it'll happen eventually."

At least two members of Congress want to make it happen sooner, rather than later.

House Oversight and Government Reform Committee chairman Darrell Issa, a California Republican, and ranking Democrat Elijah Cummings of Maryland wrote NFLPA head DeMaurice Smith this week to chastise the union for standing in the way of HGH testing and to warn that they might ask players to testify on Capitol Hill.

Smith is scheduled to hold his annual pre-Super Bowl news conference Thursday.

"We have cooperated and been helpful to the committee on all of their requests," NFLPA spokesman George Atallah said. "If this is something they feel strongly about, we will be happy to help them facilitate it."

Several players from the Super Bowl teams said they would be willing to talk to Congress about the issue, if asked.

"I have nothing to hide. I can't speak for anyone else in football, but I would have no problem going," said Kenny Wiggins, a 6-foot-6, 314-pound offensive lineman on San Francisco's practice squad.

But Wiggins added: "There's a lot more problems in the U.S. they should be worried about than HGH in the NFL."

That sentiment was echoed by former New York Giants offensive lineman Shaun O'Hara, who now works for the NFL Network.

"Do I think there is an HGH problem in the NFL? I don't think there is. Are there guys who are using it? I'm sure there are. But is it something Congress needs to worry about? No. We have enough educated people on both sides that can fully handle this. And if they can't, then they should be fired," said O'Hara, an NFLPA representative as a player. "I include the union in that, and I include the NFL. There is no reason we would need someone to help us facilitate this process."

Issa and Cummings apparently disagree.

In December, their committee held a hearing at which medical experts testified that the current HGH test is reliable and that the union's request for a new study is unnecessary. Neither the league nor union was invited to participate in that hearing; at the time, Issa and Cummings said they expected additional hearings.

"We are disappointed with the NFLPA's remarkable recalcitrance, which has prevented meaningful progress on this issue," they wrote in their recent letter to Smith. "We intend to take a more active role to determine whether the position you have taken ? that HGH is not a serious concern and that the test for HGH is unreliable ? is consistent with the beliefs of rank and file NFL players."

Atallah questioned that premise.

"To us, there is no distinction between players and the union. ... The reason we had HGH in our CBA is precisely because our players wanted us to start testing for it," Atallah said. "We are not being recalcitrant for recalcitrance sake. We are merely following the direction of our player leadership."

Wiggins and other players said no one can know for sure how much HGH use there is in the league until there is testing ? but that it's important for the union's concerns about the test to be answered.

"The union decides what is best for the players," said Ravens nose tackle Ma'ake Kemoeatu, who said he would be willing to go to Capitol Hill.

"I feel like some guys are on HGH," said 49ers offensive lineman Anthony Davis, who would rather not speak to Congress. "I personally don't care if there is testing. It's something they have to live with, knowing they cheated, and if they get (outplayed) while they're on it, it's a hit on their pride."

___

Follow Howard Fendrich on Twitter at http://twitter.com/HowardFendrich

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/347875155d53465d95cec892aeb06419/Article_2013-01-31-Super%20Bowl-HGH%20Tests/id-9ea72704fc134d3f9ea9dd5976f2ee6d

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RNA Fragments May Yield Rapid, Accurate Cancer Diagnosis

Fragments of RNA that cells eject in fatty droplets may point the way to a new era of cancer diagnosis, potentially eliminating the need for invasive tests in certain cases. Cancer tumor cells shed microvesicles containing proteins and RNA fragments, called exosomes, into cerebral spinal fluid, blood, and urine. Within these exosomes is genetic information that can be analyzed to determine the cancer?s molecular composition and state of progression. Researchers at Massachusetts General Hospital discovered that exosomes preserve the genetic information of their parent cells in 2008, however exosomes have not seen widespread clinical testing as a means of cancer diagnosis until now. ?We have never really been able to detect the genetic components of a tumor by blood or spinal fluid,? says Harvard University neurologist Fred Hochberg. ?This is really a new strategy.? He says exosome diagnostic tests could potentially detect and monitor the progression of a wide variety of cancers. He is one of the lead researchers in a multicenter clinical study using new exosomal diagnostic tests developed by New York City-based Exosome Diagnostics to identify a genetic mutation found exclusively in glioma, the most common form of brain cancer. When treating other forms of cancer, surgeons are able to biopsy tumors to diagnose and monitor the state of the disease. For brain cancers like glioma, however, multiple biopsies can be life threatening. Bob Carter, head of neurosurgery at the University of California, San Diego, says well-preserved RNA in blood and spinal fluid enables researchers to test and monitor for these genetic changes noninvasively. He says study researchers separate exosomes from bio-fluids with a diagnostic kit and then extract the relevant genomic information. Once the specific cancer mutation is identified, clinicians will periodically draw additional bio-fluids to monitor the mutation levels to determine whether a patient is responding to therapy.?? Whereas Magnetic Resonance Imaging (MRI) is a useful tool, tumors only show up on imaging scans once they are at least one millimeter in diameter and comprise about 100,000 tumor cells. By that time, it may be too late for an early intervention. On the flip side, MRIs can also yield false positives. Hochberg says individuals who have been treated with conventional radiation therapy often have benign residual tissue from dying tumor cells that have been killed by the treatment but which the body has not yet eliminated. This tissue is often mistaken for tumor growth on a MRI scan. ?You would identify to the patient that the drug is not working when in reality it is doing well,? Hochberg says. ?On the other hand, having an easily accessible biomarker for glioma would give you a clear response.? There are 18 U.S. hospitals participating in the clinical trial, sponsored by the Accelerated Brain Cancer Cure Foundation. Hochberg says study researchers have recruited 41 of 120 patients so far. Preliminary results will be presented in April at the International Society for Extracellular Vesicles Symposium in Boston. From a technical standpoint I don?t believe there is a barrier,? Carter says. ?This test can certainly be used now, what we are trying to finalize is the sensitivity and specificity of the test.? Exosomes may be a reliable method of screening for prostate cancer as well. A PSA test is currently the most common, noninvasive means to screen for prostate cancer in the U.S. PSA testing measures for elevated levels of prostate-specific antigen, a protein produced by the prostate gland that is used to liquefy semen in men. The higher a man?s PSA level, the more likely it is that he has prostate cancer, says James McKiernan, director of urologic oncology at Columbia University Medical Center. There are additional reasons, however, for high PSA levels-and some men with prostate cancer do not always have elevated PSA, he added. In addition, for many cases of prostate cancer, new research published in May 2012 in The New England Journal of Medicine shows that treatment does not actually extend the life of the patient. ?Honestly PSA is not cancer-specific,? says Sudhir Srivastava, head of the National Cancer Institute?s Cancer Biomarkers Research Group. ?Exosomes could be very much [more] cancer specific. PSA might give you one specific biomarker for cancer identification, but exosomes can give you an entire disease specific profile so you would know whether or not it is a form of prostate cancer that necessitates treatment.? Researchers at Exosome have developed a diagnostic kit for prostate cancer with a diagnostic accuracy of around 75 percent-a rate comparable with that of actually taking a tissue biopsy, says Wayne Comper, a renal physiologist and chief science officer at Exosome. He says the first diagnostic kit could be available commercially by the end of 2013. Researchers use the kit to look for the genetic biomarker TMPRSS2:ERG or T:E in exosomes taken from a urine sample. Comper says levels of T:E are nine times higher in a cancerous prostate versus a healthy one. McKiernan says researchers found these exosomal diagnostic tests gave better predictive results for cancer than current prescreening methods, such as PSA. PSA levels are measured via a blood draw but also require a visit to a doctor?s office for a digital rectal exam, something that isn?t necessary with an exosomal diagnostic test. ?Our study got enough interest to put together a series of sites for investigation to lead to potential FDA approval of this particular kit,? he says. ?That is ongoing right now and the last time I checked there were about 1,000 patients who have been enrolled in the study.? Srivastava says Exosome's prostate kit could prove to be extremely relevant in cancer treatment if it survives the U.S. Food and Drug Administration?s grueling approval process. He says it is a precursor to what he hopes will be a series of multiple-gene-signature cancer tests. ?We are looking for something with about 90 percent accuracy before it can be used by itself for clinical diagnosis,? he says. ?NCI has done two prostate trials with exosomes to date and is looking into creating standard isolation procedures to make the tests more specific.? In the meantime Srivastava says exosomal tests could be used in conjunction with current methods of diagnosis like PSA to help physicians better determine if the nature of a prostate tumor is severe enough to warrant radical treatment or removal without ever performing a biopsy. ?If someone has high PSA and also has biomarkers which are positive in exosomes that would be a great test,? he says. ?Exosomes have the potential to really further the detection of cancer and help analyze things that would have otherwise not been detected noninvasively.? ? Follow Scientific American on Twitter @SciAm and @SciamBlogs. Visit ScientificAmerican.com for the latest in science, health and technology news.
? 2013 ScientificAmerican.com. All rights reserved.

Source: http://news.yahoo.com/rna-fragments-may-yield-rapid-accurate-cancer-diagnosis-213000243.html

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Mantel's history novel picks up another major award

LONDON (Reuters) - British novelist Hilary Mantel added to her groaning trophy cabinet on Tuesday, picking up the Costa Book Award 2012 for "Bring Up the Bodies," her historical novel about the life and court of Henry VIII and his chief minister Thomas Cromwell.

The acclaimed bestseller has already won the Man Booker prize for fiction, making Mantel the first Briton and first woman to win that coveted award twice.

The 60-year-old also won the Booker Prize in 2009 for "Wolf Hall," the first instalment in what will be a trilogy.

Broadcaster Jenni Murray, chair of the nine-member panel who decided which of five Costa category winners would take the overall prize, said "Bring Up the Bodies" stood "head and shoulders" above the rest.

"This is a very difficult prize to judge, because there are five categories and they are so different," she told reporters ahead of a reception in London announcing the winner.

"It's not an easy prize to judge, but I have to say today one book simply stood head and shoulders - more than head and shoulders, on stilts - above the rest."

Mantel had been the bookmakers' favourite for the award, which comes with a cheque for 30,000 pounds ($47,000). Category winners each win 5,000 pounds.

Asked whether the judges had considered giving the prize to another author to spread the spoils of literary awards, which usually bring with them a sizeable spike in sales, she replied:

"We know this has had lots of prizes. We couldn't allow the number of times it's already been lauded to affect our decision. It was quite simply the best book."

Murray praised what she called the "poetic" prose of the novel, which traces the downfall of Anne Boleyn in 16th century England and Henry's dangerous attraction to Jane Seymour.

"It's so set in its time so you know exactly where you are and who you are with, but it's also incredibly modern," she said. "I have no doubt that I want to go back to it. I've read it twice and I want to read it again."

ALL-FEMALE SHORTLIST

"Bring Up the Bodies," which like Wolf Hall will be adapted for the stage by the Royal Shakespeare Company, was one of an all-female shortlist in 2012.

Journalist, critic and writer Francesca Segal's debut novel "The Innocents," set in a Jewish community in northwest London and modelled on Edith Wharton's "The Age of Innocence," won the Costa First Novel Award.

Scottish poet Kathleen Jamie won the poetry prize for her collection "The Overhaul," and writer/illustrator and dyslexia campaigner Sally Gardner claimed the Costa Children's Book Award for "Maggot Moon."

Husband-and-wife team Bryan and Mary Talbot jointly won the Costa Biography Award for "Dotter of her Father's Eyes," a biography of James Joyce's daughter interwoven with a memoir of the author's own troubled relationship with her father, Joycean scholar James S. Atherton.

Mary Talbot, a scholar and author, teamed up with Bryan, who has worked on underground comics and superhero stories including "Judge Dredd" and "Batman: Legends of the Dark Knight".

Their collaboration was the first graphic work to win a Costa category award.

The Costa awards go to writers based in the UK and Ireland for a work published in the last year. They were established in 1971 by Whitbread but were renamed after Costa Coffee took over the sponsorship.

The 2011 Costa Book of the Year was "Pure" by Andrew Miller.

(Reporting by Mike Collett-White)

Source: http://news.yahoo.com/mantels-history-novel-picks-another-major-award-211554469.html

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Wednesday, January 30, 2013

Video: Giffords calls for gun control in Congress hearing



>> a moment to remember back clearly to the very moment we learned about the shootings at sandy hook elementary school in newtown , connecticut. to remember how shocked we all were and how sad and sorry a scene that was. well, this is still very much the post newtown era. so there was great emotion today at a hearing on guns on capitol hill . especially when a very well-known survivor of gun violence , gabby giffords , came forward to deliver her own remarks. and yet during the hearing, we learned of another shooting. this one in arizona. a workplace, one gunman, three shooting victims, one fatal. we begin tonight with this emotional issue. our report from nbc's kelly o'donnell on capitol hill .

>> reporter: good evening, brian. the passion so deep, this hearing room was packed, included many families and survivors, victims of other shootings. and it was a group of people asking congress to do something, and that is the cause that changed the life of former congresswoman, gabby giffords , and brought her back to washington today. her gift of speech is a distant memory, said husband mark kelly . yet gabby giffords ' halting words.

>> too many children.

>> reporter: here as a survivor of the tucson assassination attempt that left her partially blind and partially paralyzed.

>> you must act. be bold, be courageous.

>> reporter: giffords and kelly, both gun owners , want congress to expand background checks to gun shows and private sales to make it harder for criminals and the mentally ill to get weapons.

>> my wife would not be sitting in this seat. she would not have been sitting here today, if we had stronger background checks .

>> reporter: but this first hearing on guns since the newtown massacre had another center of gravity . the national rifle association 's ceo, wayne lapierre .

>> should we have mandatory background checks at gun shows?

>> if you're a dealer, that's already the law.

>> reporter: of all the gun-related ideas on the table, democrats believe universal background checks has the

Source: http://video.msnbc.msn.com/nightly-news/50645616/

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Facebook Is Down (Updated)

According to users and various reports, Facebook is currently down in the US of A. As in it's not working. As in it won't even load. In fact, Facebook hasn't been working for over an hour. How in the world is the world surviving? More »


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/KGDq1ovyTPk/facebook-is-down

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Reanimating Public Education: Challenge & Futures: Alternate ...

The purpose of this first blog in a series is to propose that the present US model of a public school has hardened into a stereotype.? That model seems based on the assumptions that a K-12 school system is somehow unique, unaffected by organization theory, developments in research on human behavior irrelevant, and the only way present K-12 learning can be structured.

Paradoxically, that homogeneity of public K-12 systems contradicts the mantra of local control invoked by most public education defenders.? The specific strategic and operating environments of any organization are not usually subject to manipulation to accommodate an extant organization, though in monopolies that anti-social attempt may be made. ?Normatively, the organization is structured to deal with its environments.

This follows as well from the observation that public education in general, including its collegiate schools, has too frequently isolated itself intellectually from the basic disciplines that actually foot its practice.? Causes may be defensiveness, ignorance, fear, or just the sociology of protected, strongly associative reference group behavior augmented by the teachers? unions?? An answer would help understanding, but reality is that whatever drives present beliefs has cemented in place an over one hundred year-old model for formal organization and for envisioning critical public K-12 learning.

Subsequent posts will propose alternative K-12 models, and their implications for management of the resources powering present public primary and secondary education.

It is not absolute that the present grade, curricular structure, management arrangements, or other systems structure generally employed or present in public K-12 are wrong or automatically demand radical change.? What is assumed is that there has been far too little work executed to test the logic of present K-12 public organization.? Indeed, in the literature search for this post, fewer than 10 percent of the references viewed ? chosen from work in this century because of some reference to alternate K-12 structures ? actually explored that question.? There were five times as many references to the organization or critique of online learning.

The key suggested rule for this journey is central to creativity in any venue:? The need to temporarily suspend disbelief in options to truly scope the issues.? Detailing, critique, challenge, spotting logical holes, all come in due course to assess thinking out of the box.? But not enabling initial openness for options, simply chases any exercise back to what is already in place, creativity?s automatic disruptor.? This was illustrated this weekend by the musings of an otherwise competent, nationally recognized educator, Larry Cuban, in a post to ?The Answer Sheet,? creating a straw man to critique in the current evolution of MOOC (massive online open-source courses), versus reflecting how that innovation might in some form interact with, and nudge K-12 process.? This may be a challenge in our present US knee-jerk society, so sharpen the knives for critique, but keep them sheathed until the options are on the table.

Conventional wisdom would suggest that this journey?s topics are primarily grade span and the titles on the blocks of a school organization chart.? But conventional isn?t the melody for this song.

Organization of any human activity in both the private and public sectors in this century is either a replication of past patterns, or evolution of a past formulation, or by design, or simply occurs in an unplanned trajectory.? The latter is not as uncommon as one might believe.? Many 21st century start-ups just happen, without deliberate specification of a model for creating work, and a preconception of needed change to accommodate growth; they wind up requiring painful realignment with growth, or the lack of resilience of the start-up model drags the firm down.

Public K-12 education, not pejorative but pragmatically, has overall both ignored modern organization theory and demonstrated little awareness that, though their ?numbers? as a system have not experienced dramatic shifts, the environments for their functions and for the product they were created to nurture have dramatically changed.

For perspective, the nation?s children entering K-12 in 2013 will (at least a fraction) exit secondary education in 2025, postsecondary education and the job market by 2030.?

A data point is the sum of outputs from The World Economic Forum, meeting this past week in Davos, Switzerland.? Whether one applauds or scorns our industrial largest and most influential, their beliefs and choices will power most of our economy into the future.? Their views:? ?Climate change?will cause tremendous economic upheaval;?? ?water is the new oil;? ?one of the great concerns should be the employment effects of technology, with so many jobs being rendered obsolete by scientific or technological advances;? new technologies for analyzing the brain will change how we learn.? Pointing up the education challenge was former British Prime Minister Gordon Brown:

?

??huge advances in the Internet and technology are enabling young people to connect with each other and this is opening up the world in a way that has never happened before.? ?Young people are beginning to see that the gap between the opportunities and rights they have been promised and the opportunities and rights that are delivered to them is wholly unacceptable. And the sense that they are being deprived of these opportunities and rights is, I think, going to be the big motivating force over the next few years.?

Our scientific, technology, and even business literature now regularly assert that the knowledge and economic world, as we presently know it, won?t be a smooth extrapolation of the present.? Should it be business as usual for K-12 public education, and how it has been organized and strategized?

?

In the absence of public K-12 reinvention, a new word may be needed to describe its relevance by 2025-2030.? The calls for change in K-12 education, as perverse and ignorant as the present reform movement has been in creating the challenge, should not be a mystery.? Based on the trajectories of what today?s K-12 matriculating students will inherit by the time they are job-ready, some genuine reform is way overdue. There is a rich literature on organization theory and caveats for designing organizations.? Still, few students of the genre think in those terms, rather, using the principles and models of organization to try to explain behavior within an existing organization, or internally adjust one?s parameters to improve its outputs, or assess participant satisfaction, or its learning, or explain why one is not performing as anticipated.? But the notion of actually designing a system to do work is neither new nor does it require new tools. What it does require is a very high tolerance for inputs.? Once past the fiction that an organization is effectively described by, for example, the typical organization chart, the building material explodes.? The variables effecting an organization?s specifications are complex and layered, subject to both the internal missions of the firm and its actors, and equivalently effected by all of the exogenous factors that portray an organization?s environment, present and projectable.? The following figure tries to portray at least the chapter titles of the factors influencing an organization?s survival properties in its venue:
Most of the factors are self-explanatory though subject to major contents expansion.? The figure is color coded to try to portray the different classes of factors:? The largest frame of society and national strategy; subsidiarity, a term recently employed by California?s Governor Jerry Brown to indicate the functions that can be appropriately dedicated to the Federal or states? governments; learning variables, where DOUPP refers to knowledge ? defining, organizing, updating, prescribing, and protocols for dissemination; factors potentially controllable by a system; and the local environments that face a system.

Isn?t this unnecessarily complicating the issue of K-12 mission delivery?? Unquestionably it explodes the determinants, but when digested and hardened, the factors that impact a local system could be many of the above, but are more likely selectively and variably material to the local system.? The factors sorted can be reduced for a system based on their specific materiality.

How might the actual process of organization design work?? Again, at a conceptual level, one perspective is displayed in the diagram below.? Key assumptions of the mission, and deployment and management of resources come from recognizing the school?s major environments.? More finely tuned ?goal criteria for organization design? were detailed in the last post.? ?Organizational process? considerations were also detailed in the last post.? The triangulation of the three inputs produces something not magic, but likely some alternative forms a system might take to best reflect its environment, using the practical dimensions of what the organization is and does.
At the risk of repetition, isn?t this unnecessarily complicated?? Why change what more or less works?? Why chase scarce human resources, with time constraints through this complex process??

Multiple answers.? The process stimulates recognition of variables that impact learning goals and subsequent performance.? It would necessitate that those who manage the massive resources America devotes to public education, actually question their own beliefs and assumptions, a reality check.? It kicks those managing the system out of their comfort zones.? And it is a discovery path for alternative and more creative or productive ways to achieve learning goals consistent with a rapidly changing environment, and to use the scarce resources invested.

Where the Rubber Meets the Road

Readers with a conscientious distaste for theory and conceptualization may not find the above very satisfying, perhaps impractical, perhaps spacey??

In fact, as a long time consultant dealing with corporate strategic planning, teaching it at a high level, and doing it in my own firms managed, the process works.? Per force, the models that one can employ at a grass roots level need to be shaped and polished to work in the real organizational environments.? This post simply introduces the sweep of issues that might impact reformulating K-12 efforts.? The next several posts will seek to bore in on how some of the historically highest impact factors might fit retooling of public K-12 schools? organization.

Further, little reinvention of educational wisdom is necessarily involved, excepting the ramping discovery of better explanations for how learning works, from the neural biological and neural net simulation work underway.? In the course of research for the series, a powerhouse of existing principles for improving K-12 learning could be found.? The unifying attribute of much of that work; it did not originate in our schools of education, or in the material most frequently cited as the bases for present K-12 pedagogy.

Lastly, an example to set up the next post and demonstrate that the kind of probing above has merit.? It is likely that the closest things to widely attempted (but difficult because of uncontrolled variables) experiments to specify K-12 organization change have been the studies of grade span.? They are everywhere, even in the last century, and proliferated in this one until NCLB took hold and dominated priorities.? In the literature review for this post, one finally quit counting those studies typically executed at a system level.?

But the research results have been anything but consistent, though generally favoring a K-8/9-12 stratification over the various middle-school options.? The lack of some definitive answer has been almost universally attributed by study authors to the lack of sophisticated statistical tools that can account for concomitant and intervening variables in creating performance differences from alternate transitions.

Another point of view, the wrong question was emphasized.? The most robust finding from this population of studies has been that student performance is primarily impacted by the transitions introduced by grade span elections. Studies show transition effects appear to dissipate within roughly a year, but seemingly never asked, what specifically are the behavioral causes and effects on students from the transition(s), and precisely how do they impact current learning?? For as long as there are grades, without some functional mechanism to mitigate the losses of learning performance traceable to any transition, the child will see not just the grade span effect, but a dozen transitions. ?

One cogent explanation resides in the socialization between student and teacher that must be rebuilt at each transition;?cumulative effects of transitions might also be expected to peak for students where learning is?challenged by socioeconomic and cultural status that impedes socialization adjustments. ?Another explanation is the effect on present capacities for teacher recognition and use of prior learning, a factor that has been repeatedly empirically demonstrated to greatly influence present learning.

Viewed from the above perspectives, there may be organizational fixes for the problem; one that incorporates a longitudinal strategy will be advanced next post.

And oft-used quote, but one that never ceases to challenge how we measure accountability for K-12 by something with greater validity than a state?s school grades based on standardized tests.? By Irish poet, William Butler Yeats:? ?Education is not the filling of a pail but the lighting of a fire.? ?Designing public K-12 for that destination should be the mission. ?Part two will dig deeper to suggest how real world school organization can still be adjusted to improve the learning that will be needed in our futures.

Source: http://edunationredux.blogspot.com/2013/01/alternate-organization-of-k-12-part-one.html

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Tuesday, January 29, 2013

Newtown parents urge enforcement of gun laws

Firearms Training Unit Detective Barbara J. Mattson of the Connecticut State Police holds up a Bushmaster AR-15 rifle, the same make and model of gun used by Adam Lanza in the Sandy Hook School shooting, for a demonstration during a hearing of a legislative subcommittee reviewing gun laws, at the Legislative Office Building in Hartford, Conn., Monday, Jan. 28, 2013. The parents of children killed in the Newtown school shooting called for better enforcement of gun laws Monday at the legislative hearing. (AP Photo/Jessica Hill)

Firearms Training Unit Detective Barbara J. Mattson of the Connecticut State Police holds up a Bushmaster AR-15 rifle, the same make and model of gun used by Adam Lanza in the Sandy Hook School shooting, for a demonstration during a hearing of a legislative subcommittee reviewing gun laws, at the Legislative Office Building in Hartford, Conn., Monday, Jan. 28, 2013. The parents of children killed in the Newtown school shooting called for better enforcement of gun laws Monday at the legislative hearing. (AP Photo/Jessica Hill)

Neil Heslin, holding a picture of himself with his son Jesse, testifies at the Legislative Office Building in Hartford, Conn., Monday, Jan. 28, 2013. Neil Heslin, whose 6-year-old son Jesse Lewis was one of the 20 first-graders killed in the Dec. 14 massacre, told a legislative subcommittee reviewing gun laws that there is no need for such weapons in homes or on the streets. (AP Photo/Jessica Hill)

Neil Heslin, holding a picture of himself with his son Jesse, wipes his eye before testifying at a hearing in the Legislative Office Building in Hartford, Conn., Monday, Jan. 28, 2013. Heslin, whose 6-year-old son Jesse Lewis was one of the 20 first-graders killed in the Dec. 14 Newtown massacre, told a legislative subcommittee reviewing gun laws that there is no need for such weapons in homes or on the streets. (AP Photo/Jessica Hill)

Jeff Soracco of Oxford, Conn. wears a sticker identifying him as a responsible gun owner as he waits to sign up to speak at a hearing of a legislative subcommittee reviewing gun laws at the Legislative Office Building in Hartford, Conn., Monday, Jan. 28, 2013. The parents of children killed in the Newtown school shooting called for better enforcement of gun laws Monday at the legislative hearing. (AP Photo/Jessica Hill)

Cindy Mattioli looks toward her husband Mark as he testifies at the Legislative Office Building in Hartford, Conn., Monday, Jan. 28, 2013. Mark Mattioli whose 6-year-old son James was killed at Sandy Hook, said there are more than enough gun laws on the books, but they are not being properly enforced. (AP Photo/Jessica Hill)

(AP) ? Parents of children killed in the Newtown school shooting called for better enforcement of gun laws and tougher penalties for violators Monday at a hearing that revealed the divide in the gun-control debate, with advocates for gun rights shouting at the father of one 6-year-old victim.

Neil Heslin, whose son Jesse was killed in last month's massacre at Sandy Hook Elementary, asked people in the room to put themselves in his position as he questioned the need for any civilian to own semiautomatic, military-style weapons.

"It's not a good feeling. Not a good feeling to look at your child laying in a casket or looking at your child with a bullet wound to the forehead. It's a real sad thing," said Heslin, who held up a large framed photograph of himself and his son.

A handful of people at the packed legislative hearing then shouted about their Second Amendment rights when Heslin asked if anyone could provide a reason for a civilian to own an assault-style weapon.

"We're all entitled to our own opinions and I respect their opinions and their thoughts," Heslin said. "But I wish they'd respect mine and give it a little bit of thought."

The hearing by a legislative subcommittee reviewing gun laws offered the first public testimony by family members of those killed at Sandy Hook Elementary, where a gunman slaughtered 20 first-grade children and six women. Adam Lanza had killed his mother in their home across town and then drove to the school to carry out the shooting before committing suicide. The testimony was expected to continue late into the night.

Members of the Connecticut State Police firearms training unit brought weapons to the hearing to provide state lawmakers with a short tutorial on what's legal and illegal under the state's current assault weapons ban, passed in 1993. The group included an AR-15, the same type of rifle that was used in the Sandy Hook shooting.

Many gun rights advocates, wearing yellow stickers that read: "Another Responsible Gun Owner," were among the estimated 2,000 people at the hearing. Metal detectors were installed at the entrance to the Legislative Office Building, and some people waited as long as two hours to get into the building in Hartford.

Many spoke about the need to protect their rights and their families' safety.

"The Second Amendment does not protect our right to hunt deer," said Andrew Hesse of Middletown. "It protects our right to self-preservation and preservation of our family. The right to bear arms."

Elizabeth Drysdale, a single mother from Waterbury, spoke of three recent incidents that caused her to fear for her safety. She said she should be able to choose the size of magazine and type of firearm to defend herself.

"Don't my children and I deserve your support and consideration to be safe," she asked lawmakers.

Judy Aron of West Hartford said bills such as those requiring gun owners to have liability insurance and ammunition taxes only harm lawful gun owners.

"Every gun owner did not pull the trigger that was pulled by Adam Lanza, she said.

The state's gun manufacturers, meanwhile, urged the subcommittee to not support legislation that could put the state's historic gun manufacturing industry at risk.

Mark Mattioli, whose 6-year-old son James was killed at Sandy Hook, got a standing ovation when he said there are plenty of gun laws but they're not properly enforced. He urged lawmakers to address the culture of violence.

"It's a simple concept. We need civility across our nation," he said. "What we're seeing are symptoms of a bigger problem. This is a symptom. The problem is not gun laws. The problem is a lack of civility."

Two Southbury natives who survived a mass shooting last year at a movie theater in Aurora, Colo., urged lawmakers to address online, private guns sales that don't require background checks. Stephen Barton and Ethan Rodriguez-Torrent also want to require background checks for purchases of so-called long guns and not just handguns.

State Rep. Arthur O'Neill, R-Southbury, who has known Rodriguez-Torrent since he was a child, predicted state lawmakers will reach a compromise on guns.

He said lawmakers' minds have changed since the Dec. 14 school massacre.

"Dec. 13 was one way of looking at the world, and Dec. 15 is a different way of looking at the world," he said.

__

Follow Associated Press Writer Susan Haigh on Twitter at (at)SusanHaighAP

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2013-01-28-Connecticut%20School%20Shooting-Legislature/id-a5e331ea82ec45d1839598e121f1aed1

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Defense set in gruesome Ariz. boyfriend slaying

PHOENIX (AP) ? Jodi Arias was adamant at first. She said she knew nothing about her lover's death, didn't slit his throat, stab him nearly 30 times or put a bullet in his forehead.

Then she offered a different story: Masked intruders killed Travis Alexander and she escaped.

Arias finally settled on a third version: She had slain her abusive, on-again, off-again boyfriend in self-defense. It was kill or be killed, her attorneys told jurors during their opening statement at her ongoing trial.

However, her different stories will pose a formidable obstacle as those attorneys present their case beginning Tuesday in a Phoenix courtroom in the trial that has become a cable TV news sensation. A number of legal experts agree the primary goal for the defense will be to spare Arias the death penalty.

Brief questions posed by jurors through a judge to the lead detective as he testified could offer Arias some hope ? maybe not for acquittal but possibly to avoid becoming just the fourth woman on Arizona's death row.

Did authorities check the alibis of Alexander's roommates? Yes. Were any knives missing from sets inside his home? No. Did police find Arias in possession of the gun used in the killing? No, none of the weapons have been recovered.

The questions were previously answered during the trial but might suggest jurors aren't so sure about the prosecution's case and the theory that it was a premeditated killing ? a requirement for the death penalty.

All the defense has to do now is "feed the doubt," California jury consultant Howard Varinsky said.

The trial began in early January with all the elements needed for big play in the tabloids. Prosecutors presented pictures of the 32-year-old defendant and the victim taken on the day of the killing ? Arias nude on his bed, Alexander in the shower, then dead on the bathroom floor.

The couple's stormy courtship was replayed in court. They met in 2007 in Las Vegas. Alexander was a 30-year-old Mormon, motivational speaker and successful businessman, Arias an aspiring photographer. They dated for about five months. Arias lived in Southern California and would visit Alexander at his Mesa home.

His friends say Arias practically lived with Alexander, and that he became bothered by her possessiveness. When he broke it off, she stalked him for months, according to testimony.

She claims she ended the relationship after catching Alexander in too many lies. Still, she said she moved to Mesa at his urging after the breakup as the pair continued to have sex while he dated other women.

Arias told police that on the day of the killing, June 4, 2008, Alexander invited her to his home for sex then became enraged when she dropped his new camera while snapping photos of him. She claims she had to fight for her life.

The defense has yet to explain, however, why she put his camera and bedding in a washing machine, why she didn't call authorities; why she changed her story; and what happened to the weapons.

Alexander was shot in the head with a .25-caliber gun, the same caliber weapon that Arias' grandparents reported stolen from their California home about a week before the killing. Arias had been staying with them when the weapon was taken, authorities said.

Prosecutors say she stabbed and slashed Alexander 27 times, slit his throat, then shot him in the head in a final salvo of rage. The sheer brutality of the attack contradicts her claim of self-defense, they contend.

Defense attorneys concede that she shot Alexander and say he kept fighting, forcing her to fend him off with a knife.

In an early police interrogation of Arias, she insisted she didn't kill Alexander.

"Jodi, tell me the truth, please," Mesa police detective Esteban Flores said in the videotaped interrogation played for jurors. He noted her bloody palm print and hair were found at the scene along with the photographs that prove she was there.

"I did not kill Travis," Arias replied.

However, she said if she were to have killed him, stabbing would have been too cruel.

"I don't think I could stab him. I think I would have to shoot him until he was dead if that were my intentions," Arias told the detective. "If I had it in me to kill him, the least I could have done was make it as humane as possible."

Now that defense attorneys have said Arias did shoot Alexander, the only question is which account jurors believe.

"The truth can always be somewhere in between," said Laurie Levenson, a professor at Loyola Law School in Los Angeles and a former federal prosecutor.

Levenson said the defense will attempt to explain away everything.

In one scenario, Levenson said, defense lawyers could say Arias brought the gun from her grandparents' house but only for protection if Alexander got abusive, not to kill him. They could say she changed her stories out of fear, thinking no one would believe her, and that she was in shock after the killing so she didn't call police.

"She just needs one, just one juror to have reasonable doubt," Levenson said. "For the defense, it's going to be a victory if she doesn't end up with the death penalty."

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2013-01-28-Boyfriend%20Slaying/id-2a6d4c704db14e0182fbe76e5bba2704

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Monday, January 28, 2013

Yahoo's 4Q report shows more signs of progress

FILE - In this Friday, Jan. 25, 2013, file photo, Marissa Mayer, CEO of Yahoo!, listens during the 43rd Annual Meeting of the World Economic Forum, in Davos, Switzerland. Yahoo showed more signs of progress during the fourth quarter of 2012m, as the Internet company took advantage of higher ad prices and rising earnings from its international investments to deliver numbers that exceeded analyst forecasts. The results announced Monday, Jan 28, 2013, covered Yahoo's first full quarter under Mayer. (AP Photo/Keystone, Laurent Gillieron)

FILE - In this Friday, Jan. 25, 2013, file photo, Marissa Mayer, CEO of Yahoo!, listens during the 43rd Annual Meeting of the World Economic Forum, in Davos, Switzerland. Yahoo showed more signs of progress during the fourth quarter of 2012m, as the Internet company took advantage of higher ad prices and rising earnings from its international investments to deliver numbers that exceeded analyst forecasts. The results announced Monday, Jan 28, 2013, covered Yahoo's first full quarter under Mayer. (AP Photo/Keystone, Laurent Gillieron)

(AP) ? Yahoo showed more signs of progress during the fourth quarter as the Internet company took advantage of higher ad prices and rising earnings from its international investments to deliver numbers that exceeded analyst forecasts.

The results announced Monday covered Yahoo's first full quarter under CEO Marissa Mayer. Yahoo Inc. lured Mayer away from Google Inc. in mid-July in its latest attempt to snap out of a funk that had depressed its revenue and stock price.

The company fared well enough in the final three months of last year to produce its first full-year gain in revenue since 2008.

Yahoo is now being run by its fifth permanent or interim CEO since then. Mayer, 37, has been focusing on improving employee morale and building better mobile and social networking services so Yahoo can make more money from two of technology's hottest trends.

Her efforts so far haven't made a huge difference in Yahoo's ad sales ? the company's main way of making money. For instance, during the final three months of last year, Yahoo's revenue from search and display advertising totaled $1.07 billion, roughly the same as a year earlier.

But Yahoo's average price for display ad on its website rose 7 percent from the previous year. Meanwhile, the average price for Yahoo's search ads increased by 1 percent from the previous year. The upturn indicates advertisers believe Mayer's changes are paying off.

Investors are clearly impressed with what Mayer has been doing. Yahoo's stock gained 92 cents, or 4.5 percent, to $21.23 in extended trading. The shares are now up by 35 percent since Mayer joined the Sunnyvale, Calif., company.

Yahoo has been benefiting from its significant stakes in Yahoo Japan and China's Alibaba Group, two Internet companies that have been thriving. Yahoo's fourth-quarter income from its investments increased 17 percent from the previous year to nearly $149 million.

Overall, Yahoo's fourth-quarter earnings dipped 8 percent from the previous year to $272 million, or 23 cents per share, from $296 million, or 24 cents per share. The earnings would have been higher than the previous year, if not for a charge to close its South Korea operations and other one-time accounting items.

If not for those charges, Yahoo said it would have earned 32 cents per share. On that basis, Yahoo topped the average estimate of 27 cents per share among analysts surveyed by FactSet.

Yahoo's fourth-quarter revenue increased 2 percent from the previous year to $1.35 billion.

After subtracting advertising commissions, Yahoo's fourth-quarter revenue stood at $1.22 billion ? about $10 million above analyst forecasts.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2013-01-28-US-Earns-Yahoo/id-251dc97cf80d4c9f999d4967dc284ba1

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Qigong Improves Quality of Life for Breast Cancer Patients | Psych ...

By Janice Wood Associate News Editor
Reviewed by John M. Grohol, Psy.D. on January 27, 2013

Qigong Improves Quality of Life for Breast Cancer Patients  New research has found that qigong, an ancient Chinese mind-body practice, has been found to reduce depression and improve the quality of life in women undergoing radiation for breast cancer.

The study examined qigong in patients receiving radiation therapy and included a follow-up period to assess its benefits over time, according to researchers.

?We were [...] particularly interested to see if qigong would benefit patients experiencing depressive symptoms at the start of treatment,? said Lorenzo Cohen, Ph.D., a professor in the University of Texas M. D. Anderson Cancer Center?s Departments of General Oncology and Behavioral Science.

?It is important for cancer patients to manage stress because it can have a profoundly negative effect on biological systems and inflammatory profiles.?

For the study, Cohen and his colleagues recruited 96 women with stage 1-3 breast cancer from Fudan University Shanghai Cancer Center in Shanghai, China.

About half of the women ? 49 ? were randomly assigned to a qigong group consisting of five 40-minute classes each week during their five-to-six week course of radiation therapy. The remaining 47 women comprised a control group receiving standard care.

The program incorporated a modified version of Chinese medical qigong, which consisted of synchronizing one?s breath with various exercises, the researchers explained.

Participants in both groups completed assessments at the beginning, middle and end of radiation therapy and then one and three months later. Different aspects of quality of life were measured, including depressive symptoms, fatigue, sleep disturbances, and overall quality of life.

According to the researchers, patients in the qigong group reported a steady decline in depressive symptom scores beginning at the end of radiation therapy, with a mean score of 12.3, through the three month post-radiation follow-up with a score of 9.5. No changes were noted in the control group over time, the study found.

The study also found that qigong was especially helpful for women reporting high baseline depressive symptoms, Cohen said.

?We examined women?s depressive symptoms at the start of the study to see if women with higher levels would benefit more,? he said.

?In fact, women with low levels of depressive symptoms at the start of radiotherapy had good quality of life throughout treatment and three months later regardless of whether they were in the qigong or control group. However, women with high depressive symptoms in the control group reported the worst levels of depressive symptoms, fatigue, and overall quality of life that were significantly improved for the women in the qigong group.?

As the benefits of qigong were largely observed after treatment concluded, researchers suggest qigong may prevent a delayed symptom burden or expedite the recovery process, especially for women with elevated depressive symptoms at the start of radiation therapy. Cohen notes the delayed effect could be explained by the cumulative nature of the treatments, as the benefits often take time to be realized.

According to the researchers, the findings support other previously reported trials examining the benefits of qigong, but are too preliminary to offer clinical recommendations.

They note that additional research is needed to understand the possible biological mechanisms involved and further explore the use of qigong in ethnically diverse populations with different forms of cancer.

The study was published in the journal Cancer.

Source: University of Texas M. D. Anderson Cancer Center


APA Reference
Wood, J. (2013). Qigong Improves Quality of Life for Breast Cancer Patients. Psych Central. Retrieved on January 28, 2013, from http://psychcentral.com/news/2013/01/27/qigong-improves-quality-of-life-for-breast-cancer-patients/50826.html

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Source: http://psychcentral.com/news/2013/01/27/qigong-improves-quality-of-life-for-breast-cancer-patients/50826.html

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Garment factory fire kills 7 in Bangladesh

DHAKA, Bangladesh (AP) ? A fire swept through a two-story garment factory in Bangladesh's capital, killing at least seven female workers and injuring five others, police and fire officials said.

The fire Saturday at the Smart factory occurred just two months after a blaze killed 112 workers in another factory near the capital, raising questions about safety standards and treatment of workers in Bangladesh's $20 billion garment industry that exports clothes to leading Western retailers. The country has more than 4,000 garment factories.

The cause of the latest fire was not immediately known, fire official Abdul Halim said.

Dhaka Metropolitan Police Deputy Commissioner Monzurul Kabir said the bodies of seven women were recovered from the top floor of the factory in Dhaka's Mohammadpur district. He said the factory was making pants and shirts, but could not provide further details.

Halim said it took firefighters about two hours to bring the blaze under control.

Volunteers joined firefighters in battling the fire as a large crowd gathered outside the factory awaiting word on the fate of relatives. Family members were seen crying near the body of a female worker named Josna, who was only 16.

Earlier this month, Wal-Mart Stores Inc. alerted its global suppliers that it will immediately drop them if they subcontract their work to factories that haven't been authorized by the discounter. The stricter contracting rule, along with other changes to its policy, come amid increasing calls for better safety oversight after the deadly fire in late November at a factory owned by Tazreen Fashions Ltd. that supplied clothing to Wal-Mart and other retailers. Wal-Mart has said the factory wasn't authorized to make its clothes.

Wal-Mart ranks second behind Swedish fast fashion retailer H&M in the number of clothing orders it places in Bangladesh. Before the November fire, Wal-Mart had taken steps to address safety, such as mandating fire safety training for all levels of factory management.

Building fires have led to more than 600 deaths of garment workers in Bangladesh since 2005, according to research by the advocacy group International Labor Rights Forum.

Source: http://news.yahoo.com/garment-factory-fire-kills-7-bangladesh-201555103.html

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Sunday, January 27, 2013

Relocation Sales Manager - InsuranceSalesWeb.com


Sales manager is a corporate salesperson in charge of building a book of business within an assigned territory designation. The position involves selling a portfolio of products and services to meet the needs of business travelers, expatriates and foreign nationals. Channels for sales development include corporate accounts, large relocation and travel groups, airlines, insurance brokers, banks and affinity groups. The sales manager must be flexible and experienced with a variety of skills including direct and business-to-business sales, account management, new business development and third party account management. He/she will acquire clients for our company by developing corporate or group prospects.

The position requires account management skills. He/she will be responsible for managing and expanding our existing and prospective client base. The sales manager will need to ensure the accuracy of regional files and the database of accounts in his/her respective territory. He/she will also be responsible for coordinating back office logistics. The sales manager is responsible for soliciting business by sending out company collateral, responding to inquiries, going on sales calls, developing and negotiating contracts, running reports and developing proposals.

Position Requirements
Position requires 3 to 5 years previous sales experience and a combination of excellent oral and written communication skills. Previous global mobility industry or insurance industry experience preferred. The candidate must have good people skills, patience and flexibility. He/she must be responsible, persuasive, confident and reflect well upon our business. The position calls for the ability to work creatively, independently and manage detail. Computer literacy is required along with knowledge of word processing, PowerPoint, Excel and database software.

Bachelor?s degree or equivalent sales experience
Multilingual abilities are a plus.

About Us
Chartis is a world leading property-casualty and general insurance organization serving more than 40 million clients in over 160 countries and jurisdictions. With a 90-year history, one of the industry's most extensive ranges of products and services, deep claims expertise and excellent financial strength, Chartis enables its commercial and personal insurance clients alike to manage virtually any risk with confidence. For additional information, please visit our website at http://www.Chartisinsurance.com.

At Chartis we support and encourage a diverse work environment. EOE.

Requisition #: 81371

Source: http://jobs.insurancesalesweb.com/c/job.cfm?site_id=1636&jb=12108392

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NYC mayor tops $1B in gifts to Johns Hopkins Univ. (Providence Journal)

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APNewsBreak: Harkin won't seek 6th Senate term

In this Monday, Oct. 25, 2010 photo, U.S. Sen. Tom Harkin, D-Iowa, speaks to reporters following a rally in support of three Iowa Supreme Court justices who are up for retention votes in the November election, in Des Moines, Iowa. Harkin says he will not seek re-election in 2014, The Associated Press reports Saturday, Jan. 26, 2013. (AP Photo/Charlie Neibergall)

In this Monday, Oct. 25, 2010 photo, U.S. Sen. Tom Harkin, D-Iowa, speaks to reporters following a rally in support of three Iowa Supreme Court justices who are up for retention votes in the November election, in Des Moines, Iowa. Harkin says he will not seek re-election in 2014, The Associated Press reports Saturday, Jan. 26, 2013. (AP Photo/Charlie Neibergall)

(AP) ? U.S. Sen. Tom Harkin said Saturday he will not seek a sixth term in 2014, a decision that eases some of the burden the national Republican Party faces in retaking the Senate.

Harkin, chairman of an influential Senate committee, announced his decision during an interview with The Associated Press, saying the move could surprise some.

The 73-year-old cited his age ? he would be 81 at the end of a sixth term ? as a factor in the decision, saying it was time to pass the torch he has held for nearly 30 years, freeing a new generation of Iowa Democrats to seek higher office.

"I just think it's time for me to step aside," Harkin told the AP.

Harkin, first elected in 1984, ranks seventh in seniority and fourth among majority Democrats. He is chairman of the Health, Education, Labor and Pensions Committee, and chairman of the largest appropriations subcommittee.

Harkin has long aligned with the Senate's more liberal members, and his signature legislative accomplishment is the 1990 Americans with Disabilities Act. He also served as a key salesman of President Barack Obama's health care overhaul to the wary left.

"I'm not saying that giving this up and walking away is easy. It's very tough," Harkin said at his rural Iowa home south of Des Moines. "But I'm not quitting today. I'm not passing the torch sitting down."

Harkin's news defied outward signals. Besides being beloved in his party, Harkin has $2.7 million in his campaign war chest, second most among members nearing the end of their terms, and was planning a fundraiser in Washington, D.C., next month featuring pop star Lady Gaga.

Obama released a statement saying Harkin will be missed and thanking the senator for his service. "During his tenure, he has fought passionately to improve quality of life for Americans with disabilities and their families, to reform our education system and ensure that every American has access to affordable health care," Obama said.

Although members of his family have been diagnosed with cancer, Harkin said his health is good ? and reported a recent positive colonoscopy. But he said "you never know," and that he wanted to travel and spend his retirement with his wife, Ruth, "before it's too late."

He also nodded to his political longevity: "The effect of that cascades down and it opens a lot of doors of opportunity" for future candidates.

But by opening a door in Iowa, Harkin has created a potential headache for his party nationally.

Democrats likely would have had the edge in 2014 with the seat, considering Harkin's fundraising prowess and healthy approval. A poll by the Des Moines Register last fall showed a majority of Iowans approved of his job performance.

Democrats hold a 55-45 advantage in the Senate, requiring Republicans to gain six seats to win back the chamber. But Democrats have more seats to defend in 2014 ? 20 compared with only 13 for Republicans. Historically, the president's party loses seats in the midterm elections after his re-election.

In GOP-leaning West Virginia, five-term Democratic Sen. Jay Rockefeller recently announced he would not seek re-election. And on Friday, Georgia Sen. Saxby Chambliss, a Republican, announced that he wouldn't seek a third term.

Democratic incumbents also face tough re-election races in Arkansas, Louisiana, Montana, North Carolina and Alaska ? all carried by Republican Mitt Romney in November's presidential election.

Harkin's move opens a rare open Senate seat Iowa. Harkin, Iowa's junior senator, is outranked by Sen. Charles Grassley, who has held the state's other seat since 1980.

Attention will turn to U.S. Rep. Bruce Braley, a fourth-term Democrat from Waterloo who has long been mentioned as a possible Harkin successor. Braley, who was traveling in Iowa, did not immediately return requests by the AP for comments beyond an emailed statement calling Harkin a "mentor" and "progressive force" who leaves "a legacy few will ever match."

Harkin held open the possibility of endorsing a Democrat before the primary if the candidate "is a pragmatic progressive."

Although no Republicans have stepped forward, Harkin's news gives the GOP's private huddles new life.

"There are lots of conversations, but it's very early still," said Nick Ryan, an Iowa Republican campaign fundraiser.

U.S. Rep. Tom Latham of Clive is a seasoned Republican congressman, a veteran House Appropriations Committee member and a robust fundraiser who has won 10 consecutive terms. Aides to Latham declined to comment beyond a statement saying the congressman "respects Sen. Harkin's decision (and) looks forward to continuing to work with him."

Since November, Harkin has stepped up his role as one of the Senate's leading liberal populists.

He was a vocal opponent late last year of Obama's concession to lift the income threshold for higher taxes to avoid the so-called fiscal cliff. Harkin instead supported raising taxes on all earners making more than $250,000 a year.

He also endorsed Obama's call for banning assault rifles and larger ammunition magazines after the Connecticut school shooting.

Despite Harkin's strong political position, he has faced questions about his and his wife's role in developing a namesake policy institute at Iowa State University, Harkin's alma mater. The Harkins and their supporters have been pushing for the institute to house papers highlighting his signature achievements, including the ADA and shaping farm policy as the former chairman of the Agriculture Committee.

Harkin has avoided questions about fundraising for the institute after disclosure reports showed some of its largest donors are firms that have benefited from his policies.

Harkin dismissed that those questions had any bearing on his decision.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2013-01-26-Harkin-Iowa/id-c221e6a0054147d4a9a88a84f0001103

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